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Preface
Major advances have occurred in the management of pediatric solid tumors of infants and children in the last several years. New information is available regarding their diagnosis, and in some cases ne...
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Robert C. Shamberger
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1
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Neuroblastoma
Neuroblastoma is a heterogeneous disease; tumors can spontaneously regress or mature, or display an aggressive, therapy-resistant phenotype. Increasing evidence indicates that the biological and molec...
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Andrew M. Davidoff
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2-14
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Wilms tumor: recent advances in clinical care and biology
Wilms tumor is the most common renal malignancy that occurs in childhood. The remarkable evolution of treatment for this malignancy has served as a paradigm for multimodal cancer treatment. A rich dat...
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Thomas E. Hamilton,
Robert C. Shamberger
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15-20
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Hepatoblastoma: recent developments in research and treatment
Hepatoblastoma is the most common liver tumor of early childhood. According to recent studies its incidence seems to be increasing in North America and Europe. Since new histological variants have bee...
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Dietrich von Schweinitz
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21-30
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Pediatric gastrointestinal stromal tumor
Pediatric gastrointestinal stromal tumor (GIST) is a rare entity that can be quite different from its adult counterpart. This report provides a comprehensive review on the diagnosis and management of ...
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Katherine A. Janeway,
Christopher B. Weldon
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31-43
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Pediatric thyroid cancer
Thyroid cancer is an uncommon childhood malignancy that presents primarily in young children or adolescent females and may be related to radiation exposure or genetic predisposition. Gene alterations,...
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Diana L. Diesen,
Michael A. Skinner
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44-50
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Pediatric germ cell tumors
Pediatric germ cell tumors represent a diverse group of tumors that present from in utero through adolescence at many nongonadal locations, from the neck to the sacrococcygeal region. Surgical resecti...
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Frederick J. Rescorla
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51-60
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Recent advances in non-rhabdomyosarcoma soft-tissue sarcomas
Nonrhabdomyosarcoma soft-tissue sarcomas (NRSTS) represent a subgroup of sarcomas that encompass more than 50 distinct histologies. All are rare, but some are more common in patients younger than 20 y...
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Andrea Hayes-Jordan
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61-67
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Update on rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is a malignant childhood tumor of mesenchymal origin that currently has a greater than 70% overall 5-year survival. Multimodality treatment is determined by risk stratification ...
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Roshni Dasgupta,
David A. Rodeberg
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68-78
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Surgical treatment of lung metastases in patients with embryonal pediatric solid tumors: an update
Distant metastases regularly occur in children with solid tumors. The most affected organ is the lung. Nearly in all extracranial pediatric solid tumors, the presence of lung metastases is associated ...
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Joerg Fuchs,
Guido Seitz,
Rupert Handgretinger,
Juergen Schäfer,
Steven W. Warmann
et al.
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79-87
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The role of neoadjuvant chemotherapy in children with malignant solid tumors
Pediatric surgeons play a critical role in diagnosing, staging, and treating malignant solid tumors in children. Over the years, the surgical management of the primary tumor site has evolved from an a...
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Andrew M. Davidoff,
Israel Fernandez-Pineda,
Victor M. Santana,
Stephen J. Shochat
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88-99
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