Seminars in Pediatric Surgery
Volume 16, Issue 3 , Pages 154-163 , August 2007

Pathology of inflammatory bowel disease

  • Terry Gramlich, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests and correspondence: Terry Gramlich, MD, AmeriPath’s Institute of Gastrointestinal Pathology and Digestive Disease, 7730 First Place, Suite A, Oakwood Village, OH 44146.
    • ,
  • Robert E. Petras, MD

References 

  1. Petras R. Non-neoplastic intestinal diseases. In:  Mills SE editors. Sternberg’s Diagnostic Surgical Pathology. (4th ed.). Philadelphia, PA: Lippincott, Williams & Wilkins; 2004;p. 1475–1541
  2. Warren S, Sommers SC. Pathology of regional ileitis and ulcerative colitis. J Am Med Assoc. 1954;154:189–193
  3. Farmer RG, Hawk WA, Turnbull RB. Regional enteritis of the colon: a clinical and pathologic comparison with ulcerative colitis. Am J Dig Dis. 1968;13:501–514
  4. Farmer M, Petras RE, Hunt LE, et al. The importance of diagnostic accuracy in colonic inflammatory bowel disease. Am J Gastroenterol. 2000;95:3184–3188
  5. Rudolph WG, Uthoff SMS, McAuliffe TL, et al. Indeterminate colitis: the real story. Dis Colon Rectum. 2002;45:1528–1534
  6. Goldman H, Antonioli DA. Mucosal biopsy of the rectum, colon and distal ileum. Hum Pathol. 1982;13:981–1012
  7. Seldenrijk CA, Morson BC, Meuwissen SGM, et al. Histopathological evaluation of colonic mucoasl biopsy specimens in chronic inflammatory bowel disease: diagnostic implications. Gut. 1991;32:1514–1520
  8. Surawicz CM, Belic L. Rectal biopsy helps to distinguish acute self-limited colitis from idiopathic inflammatory bowel disease. Gastroenterology. 1984;86:104–113
  9. Norstrant TT, Kumar NB, Appelman HD. Histopathology differentiates acute self-limited colitis from ulcerative colitis. Gastroenterology. 1987;92:318–328
  10. Volk EE, Shapiro BD, Easley KA, et al. The clinical significance of a biopsy-based diagnosis of focal active colitis: a clinicopathologic study of 31 cases. Mod Pathol. 1998;11:789–794
  11. Xin W, Brown PI, Greenson JK. The clinical significance of focal active colitis in pediatric patients. Am J Surg Pathol. 2003;27:1134–1138
  12. Markowitz J, Kahn E, Grancher K, et al. Atypical rectosigmoid histology in children with newly diagnosed ulcerative colitis. Am J Gastroenterol. 1993;88:2037
  13. Glickman JN, Bousvaros A, Farraye FA, et al. Pediatric patients with intreated ulcerative colitis may present initially with unusual morphologic findings. Am J Surg Pathol. 2004;28:190–197
  14. Washington K, Greenson JK, Montgomery E, et al. Histopathology of ulcerative colitis in initial rectal biopsy in children. Am J Surg Pathol. 2002;26:1441–1449
  15. Odze R, Antonioli D, Peppercorn M, et al. Effect of topical 5-aminosalicylic acid (5-ASA) therapy on rectal mucosal biopsy morphology in chronic ulcerative colitis. Am J Surg Pathol. 1993;17:869–875
  16. Surawicz CM. Mucosal biopsy diagnosis of colitis. Semin Colon Rectal Surg. 1992;3:154–159
  17. Levine TS, Tzardi M, Mitchell S, et al. Diagnostic difficulty arising from rectal recovery in ulcerative colitis. J Clin Pathol. 1996;49:319–323
  18. Valdez R, Appelman HD, Bronner MP, et al. Diffuse duodenitis associated with ulcerative colitis. Am J Surg Pathol. 2000;24:1407–1413
  19. Shapiro JL, Goldblum JR, Petras RE. A clinicopathologic study of 42 cases of granulomatous gastritis: is there really an isolated granulomatous gastritis?. Am J Surg Pathol. 1996;20:462–470
  20. Sharif F, McDermott M, Dillon M, et al. Focally enhanced gastritis in children with Crohn’s disease and ulcerative colitis. Am J Gastroenterol. 2002;97:1415–1420
  21. Pascasio JM, Hammond S, Qualman SJ. Recognition of Crohn’s disease on incidental gastric biopsy in childhood. Pediatr Dev Pathol. 2003;6:209–214
  22. McIntyre PB, Pemberton JH, Wolff BG, et al. Indeterminate colitis: long-term outcome in patients after ileal pouch-anal anastomosis. Dis Colon Rectum. 1995;38:51–54
  23. Phillips RKS. Ileal pouch-anal anastomosis for Crohn’s disease. Gut. 1998;43:303–308
  24. Alexander F, Sarigol S, DiFiore J, et al. Fate of the pouch in 151 pediatric patients after ileal pouch anal anastomosis. J Pediatr Surg. 2003;38:78–82
  25. Petras R, Oakley J. Intestinal complications of inflammatory bowel disease: pathologic aspects. Semin Colon Rect Surg. 1992;3:160–172
  26. Delaney C, Remzi F, Gramlich T, et al. Equivalent function, quality of life and pouch survival rates after ileal pouch-anal anastamosis for indeterminate and ulcerative colitis. Ann Surg. 2002;236:43–48
  27. LeBerre N, Heresback O, Kerbaol M, et al. Histological discrimination of idiopathic inflammatory bowel disease from other types of colitis. J Clin Pathol. 1995;48:749–753
  28. Price AB, Davies DR. Pseudomembranous colitis. J Clin Pathol. 1977;30:1–12
  29. Gremse DA, Boudreaux CW, Manci EA. Collagenous colitis in chilren. Gastroenterology. 1993;104:906–909
  30. Wang N, Dumot JA, Achkar E, et al. Colonic epithelial lymphocytosis without a thickened subepithelial collagen table: a clinical pathologic study of 40 cases supporting a heterogenious entity. Am J Surg Pathol. 1999;23:1068–1074
  31. Goldstein NS, Gyorfi T. Focal lymphocytic colitis and collagenous colitis: patterns of Crohn’s colitis?. Am J Surg Pathol. 1999;23:1075–1081
  32. Makapugay LM, Dean PJ. Diverticular disease-associated chronic colitis. Am J Surg Pathol. 1996;20:94–102
  33. Warren BF, Shepherd NA, Bartolo DC, et al. Pathology of the defunctioned rectum in ulcerative colitis. Gut. 1993;34:514–516
  34. Asplund S, Gramlich T, Fazio V, et al. Histologic changes in defunctioned rectums in patients with inflammatory bowel disease: a clinicopathologic study of 82 patients with long follow-up. Dis Colon Rectum. 2002;45:1206–1213
  35. Grant NJ, Van Kruiningen HJ, Haque S, et al. Mucosal inflammation in pediatric diversion colitis: a quantitative analysis. J Pediatr Gastroenterol Nutr. 1997;25:273–280
  36. Sandborn WJ. Pouchitis following ileal pouch-anal anastomosis: definition, pathogenesis, and treatment. Gastroenterology. 1994;107:1856–1860
  37. Petras R. Role of the pathologist in evaluating chronic pouches. In:  Hanauer SB,  Bayless TM editor. Advanced Therapy of Inflammatory Bowel Disease. (2nd ed.). Hamilton, ON: BC Decker; 2001;p. 229–232
  38. Shepherd NA, Jass JR, Duval I, et al. Restorative proctocolectomy with ileal reservoir: pathologic and histochemical study of mucosal biopsy specimens. J Clin Pathol. 1987;40:601–607
  39. Sarigol S, Wyllie R, Gramlich T, et al. Incidence of dysplasia in pelvic pouches in pediatric patients after ileal pouch-anal anastomosis for ulcerative colitis. J Pediatr Gastroenterol Nutr. 1999;28:429–434
  40. Riddell R, Goldman H, Ransohoff D, et al. Dysplasia in inflammatory bowel disease: standardized classification with provisional applications. Hum Pathol. 1983;14:931–968
  41. Riddell RH, Petras RE, Williams GT, et al. Tumors of the intestines. In: Atlas of Tumor Pathology Third Series Fascicle #32. Washington DC: Armed Forces Institute of Pathology; 2003;p. 189–200
  42. Rosenstock E, Farmer RG, Petras R, et al. Surveillance for colonic carcinoma in ulcerative colitis. Gastroenterology. 1985;89:1342–1346
  43. Petras RE. The significance of “adenomas” and ulcerative colitis: deciding when a colectomy should be performed. Inflammatory Bowel Disease. 1999;5:306–308
  44. Odze RD, Farraye FA, Hecht JL, et al. Long-term follow-up after polypectomy treatment for adenoma-like dysplastic lesions in ulcerative colitis. Clin Gastroenterol Hepatol. 2004;2:534–541
  45. Hamilton SR. Colorectal carcinoma in patients with Crohn’s disease. Gastroenterology. 1985;89:398–407
  46. Segal JE, Petras RE, Lashner BA, et al. Intestinal adenocarcinoma in Crohn’s disease: a report of 30 cases with a focus on co-existing dysplasia. Am J Surg Pathol. 1999;23:651–655
  47. Petras RE, Mir-Madjlessi SH, Farmer RG. Crohn’s disease in intestinal carcinoma: a report of 11 cases with emphasis on associated epithelial dysplasia. Gastroenterology. 1987;93:1304–1307

PII: S1055-8586(07)00022-4

doi: 10.1053/j.sempedsurg.2007.04.005

Seminars in Pediatric Surgery
Volume 16, Issue 3 , Pages 154-163 , August 2007

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