Seminars in Pediatric Surgery
Volume 15, Issue 3 , Pages 162-169 , August 2006

Growth after organ transplantation

  • John S. Fuqua, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests and correspondence: John S. Fuqua, MD, Section of Pediatric Endocrinology and Diabetology, Indiana University School of Medicine, Riley Hospital for Children, 702 Barnhill Drive, Room 5960, Indianapolis, IN 46202.

References 

  1. Schulak JA . What’s new in general surgery (transplantation) . J Am Coll Surg . 2005;200:409–417
  2. Berardinelli L , Ferraresso M , Raiteri M , et al.   Twenty-six year surgical experience of 259 pediatric transplants in 235 children and long-term follow-up of 181 under cyclosporine therapy . Transplant Proc . 1998;30:1977–1979
  3. Burdelski M , Nolkemper D , Ganschow R , et al.   Liver transplantation in children (long-term outcome and quality of life) . Eur J Pediatr . 1999;158(suppl 2):S34–S42
  4. Blume ED . Current status of heart transplantation in children (update 2003) . Pediatr Clin North Am . 2003;50:1375–1391
  5. Le Roith D , Scavo L , Butler A . What is the role of circulating IGF-I? . Trends Endocrinol Metab . 2001;12:48–52
  6. Fine RN . Growth following solid-organ transplantation . Pediatr Transplant . 2002;6:47–52
  7. Brown J , Zacharin M . Proposals for prevention and management of steroid-induced osteoporosis in children and adolescents . J Paediatr Child Health . 2005;41:553–557
  8. Tonshoff B , Haffner D , Mehls O , et al.   Efficacy and safety of growth hormone treatment in short children with renal allografts: three year experience. Members of the German Study Group for Growth Hormone Treatment in Children with Renal Allografts . Kidney Int . 1993;44:199–207
  9. Tejani A , Fine R , Alexander S , et al.   Factors predictive of sustained growth in children after renal transplantation. The North American Pediatric Renal Transplant Cooperative Study . J Pediatr . 1993;122:397–402
  10. Neu AM , Ho PL , McDonald RA , et al.   Chronic dialysis in children and adolescents. The 2001 NAPRTCS Annual Report . Pediatr Nephrol . 2002;17:656–663
  11. Turenne MN , Port FK , Strawderman RL , et al.   Growth rates in pediatric dialysis patients and renal transplant recipients . Am J Kidney Dis . 1997;30:193–203
  12. Craig J, Cowell C, Knight J. Growth hormone for children with chronic renal failure. The Cochrane Database of Systematic Reviews, Last updated February 24, 2005. Accessed December 12, 2005. Available from: http://www.cochrane.org/reviews/en/ab003264.html.
  13. Bartosh SM , Thomas SE , Sutton MM , et al.   Linear growth after pediatric liver transplantation . J Pediatr . 1999;135:624–631
  14. McDiarmid SV , Gornbein JA , DeSilva PJ , et al.   Factors affecting growth after pediatric liver transplantation . Transplantation . 1999;67:404–411
  15. Orii T , Ohkohchi N , Koyamada N , et al.   Growth of pediatric patients with biliary atresia after liver transplantation (influence of age at transplantation and steroid administration) . Transplant Proc . 2000;32:2210–2212
  16. Pasqualini T , Ferraris JR , Jasper H , et al.   Differences in anthropometric parameters and the IFG-I-IGFBP3 axis between liver and renal transplant children . Transplantation . 2000;70:472–476
  17. Falkenstein K , Dunn S . Growth acceleration on cyclosporine monotherapy after liver transplantation in children . Transplant Proc . 1998;30:1969–1972
  18. Rodeck B , Melter M , Hoyer PF , et al.   Growth in long-term survivors after orthotopic liver transplantation in childhood . Transplant Proc . 1994;26:165–166
  19. Group SR . Studies of Pediatric Liver Transplantation (SPLIT) (year 2000 outcomes) . Transplantation . 2001;72:463–476
  20. Au J , Gregory JW , Colquhoun IW , et al.   Paediatric cardiac transplantation with steroid-sparing maintenance immunosuppression . Arch Dis Child . 1992;67:1262–1266
  21. Tyden G , Berg U , Bohlin AB , et al.   Renal transplantation in children less than two years old . Transplantation . 1997;63:554–558
  22. Nissel R , Brazda I , Feneberg R , et al.   Effect of renal transplantation in childhood on longitudinal growth and adult height . Kidney Int . 2004;66:792–800
  23. Rodriguez-Soriano J , Vallo A , Quintela MJ , et al.   Predictors of final adult height after renal transplantation during childhood (a single-center study) . Nephron . 2000;86:266–273
  24. van Diemen-Steenvoorde R , Donckerwolcke RA , Brackel H , et al.   Growth and sexual maturation in children after kidney transplantation . J Pediatr . 1987;110:351–356
  25. Maxwell H , Haffner D , Rees L . Catch-up growth occurs after renal transplantation in children of pubertal age . J Pediatr . 1998;133:435–440
  26. Ferraris JR , Pasqualini T , Legal S , et al.  The Deflazacort Study Group   Effect of deflazacort versus methylprednisone on growth, body composition, lipid profile, and bone mass after renal transplantation . Pediatr Nephrol . 2000;14:682–688
  27. Scharer K , Feneberg R , Klaus G , et al.   Experience with deflazacort in children and adolescents after renal transplantation . Pediatr Nephrol . 2000;14:457–463
  28. Birkeland SA , Larsen KE , Rohr N . Pediatric renal transplantation without steroids . Pediatr Nephrol . 1998;12:87–92
  29. Kapila P , Jones J , Rees L . Effect of chronic renal failure and prednisolone on the growth hormone-insulin-like growth factor axis . Pediatr Nephrol . 2001;16:1099–1104
  30. Friedman AL . Growth hormone is not safe for children with renal transplants . J Pediatr . 1997;131:S25–S27
  31. Rees L , Maxwell H . Factors influencing the response to growth hormone in children with renal disease . Pediatr Nephrol . 1996;10:337–339
  32. Maxwell H , Dalton RN , Nair DR , et al.   Effects of recombinant human growth hormone on renal function in children with renal transplants . J Pediatr . 1996;128:177–183
  33. Mentser M , Breen TJ , Sullivan EK , et al.   Growth-hormone treatment of renal transplant recipients (the National Cooperative Growth Study experience–a report of the National Cooperative Growth Study and the North American Pediatric Renal Transplant Cooperative Study) . J Pediatr . 1997;131:S20–S24
  34. Tyden G , Berg U , Reinholt F . Acute renal graft rejection after treatment with human growth hormone . Lancet . 1990;336:1455–1456
  35. Schwartz ID , Warady BA . Cadaveric renal allograft rejection after treatment with recombinant human growth hormone . J Pediatr . 1992;121:664–666
  36. Tyden G , Reinholt FP , Berg U , et al.   Acute graft rejection after treatment with human growth hormone . Transplantation . 1997;63:174–176
  37. Chavers BM , Doherty L , Nevins TE , et al.   Effects of growth hormone on kidney function in pediatric transplant recipients . Pediatr Nephrol . 1995;9:176–181
  38. Kelley KW . The role of growth hormone in modulation of the immune response . Ann N Y Acad Sci . 1990;594:95–103
  39. Hokken-Koelega AC , Stijnen T , de Jong RC , et al.   A placebo-controlled, double-blind trial of growth hormone treatment in prepubertal children after renal transplant . Kidney Int Suppl . 1996;53:S128–S134
  40. Guest G , Berard E , Crosnier H , et al.   Effects of growth hormone in short children after renal transplantation. French Society of Pediatric Nephrology . Pediatr Nephrol . 1998;12:437–446
  41. Maxwell H , Rees L . Randomised controlled trial of recombinant human growth hormone in prepubertal and pubertal renal transplant recipients. British Association for Pediatric Nephrology . Arch Dis Child . 1998;79:481–487
  42. Fine RN , Stablein D , Cohen AH , et al.   Recombinant human growth hormone post-renal transplantation in children (a randomized controlled study of the NAPRTCS) . Kidney Int . 2002;62:688–696
  43. Broyer M  Pharmacia & Upjohn Study Group . Results and side-effects of treating children with growth hormone after kidney transplantation–a preliminary report . Acta Paediatr Suppl . 1996;417:76–79
  44. Hokken-Koelega AC , Stijnen T , de Ridder MA , et al.   Growth hormone treatment in growth-retarded adolescents after renal transplant . Lancet . 1994;343:1313–1317
  45. Laine J , Krogerus L , Sarna S , et al.   Recombinant human growth hormone treatment. Its effect on renal allograft function and histology . Transplantation . 1996;61:898–903
  46. Tyden G , Wernersson A , Sandberg J , et al.   Development of renal cell carcinoma in living donor kidney grafts . Transplantation . 2000;70:1650–1656
  47. Codoner-Franch P , Bernard O , Alvarez F . Long-term follow-up of growth in height after successful liver transplantation . J Pediatr . 1994;124:368–373
  48. Renz JF , de Roos M , Rosenthal P , et al.   Posttransplantation growth in pediatric liver recipients . Liver Transpl . 2001;7:1040–1055
  49. van Mourik ID , Beath SV , Brook GA , et al.   Long-term nutritional and neurodevelopmental outcome of liver transplantation in infants aged less than 12 months . J Pediatr Gastroenterol Nutr . 2000;30:269–275
  50. Sarna S , Sipila I , Jalanko H , et al.   Factors affecting growth after pediatric liver transplantation . Transplant Proc . 1994;26:161–164
  51. Sarna S , Hoppu K , Neuvonen PJ , et al.   Methylprednisolone exposure, rather than dose, predicts adrenal suppression and growth inhibition in children with liver and renal transplants . J Clin Endocrinol Metab . 1997;82:75–77
  52. Sarna S , Sipila I , Vihervuori E , et al.   Growth delay after liver transplantation in childhood (studies of underlying mechanisms) . Pediatr Res . 1995;38:366–372
  53. McDiarmid SV , Anand R , Lindblad AS . Studies of Pediatric Liver Transplantation: 2002 update. An overview of demographics, indications, timing, and immunosuppressive practices in pediatric liver transplantation in the United States and Canada . Pediatr Transplant . 2004;8:284–294
  54. Diem HV , Sokal EM , Janssen M , et al.   Steroid withdrawal after pediatric liver transplantation (a long-term follow-up study in 109 recipients) . Transplantation . 2003;75:1664–1670
  55. Sarna S , Laine J , Sipila I , et al.   Differences in linear growth and cortisol production between liver and renal transplant recipients on similar immunosuppression . Transplantation . 1995;60:656–661
  56. Sarna S , Sipila I , Ronnholm K , et al.   Recombinant human growth hormone improves growth in children receiving glucocorticoid treatment after liver transplantation . J Clin Endocrinol Metab . 1996;81:1476–1482
  57. Puustinen L , Jalanko H , Holmberg C , et al.   Recombinant human growth hormone treatment after liver transplantation in childhood (the 5-year outcome) . Transplantation . 2005;79:1241–1246
  58. LeBidois J , Kachaner J , Vouhe P , et al.   Heart transplantation in children (mid-term results and quality of life) . Eur J Pediatr . 1992;151(suppl 1):S59–S64
  59. Fleisher BE , Baum D , Brudos G , et al.   Infant heart transplantation at Stanford (growth and neurodevelopmental outcome) . Pediatrics . 2002;109:1–7
  60. Cohen A , Addonizio LJ , Softness B , et al.   Growth and skeletal maturation after pediatric cardiac transplantation . Pediatr Transplant . 2004;8:126–135
  61. Chinnock R , Baum M . Somatic growth in infant heart transplant recipients . Pediatr Transplant . 1998;2:30–34
  62. Nucci AM , Barksdale EM , Beserock N , et al.   Long-term nutritional outcome after pediatric intestinal transplantation . J Pediatr Surg . 2002;37:460–463
  63. Sudan DL , Iverson A , Weseman RA , et al.   Assessment of function, growth and development, and long-term quality of life after small bowel transplantation . Transplant Proc . 2000;32:1211–1212
  64. Rovera GM , Strohm S , Bueno J , et al.   Nutritional monitoring of pediatric intestinal transplant recipients . Transplant Proc . 1998;30:2519–2520
  65. Sweet SC , Spray TL , Huddleston CB , et al.   Pediatric lung transplantation at St. Louis Children’s Hospital, 1990-1995 . Am J Respir Crit Care Med . 1997;155:1027–1035

PII: S1055-8586(06)00027-8

doi: 10.1053/j.sempedsurg.2006.03.003

Seminars in Pediatric Surgery
Volume 15, Issue 3 , Pages 162-169 , August 2006