Seminars in Pediatric Surgery
Volume 15, Issue 1 , Pages 30-36 , February 2006

Malignant germ cell tumors in childhood

  • Deborah F. Billmire, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests and correspondence: Deborah F. Billmire, 702 Barnhill Drive, Room 2500, Indianapolis, IN 46202

References 

  1. Lo Curto M , Lumia F , Alaggio R , et al.   Malignant germ cell tumors in childhood (results of the first Italian cooperative study “TCG 91) . ” Med Pediatr Oncol . 2003;41:417–425
  2. Göbel U , Schneider DT , Calaminus G , et al.   Germ-cell tumors in childhood and adolescence . Ann Oncol . 2000;11:263–271
  3. Billmire D , Vinocur C , Rescorla F , et al.   Malignant mediastinal germ cell tumors (an intergroup study) . J Pediatr Surg . 2001;36:18–24
  4. Billmire D , Vinocur C , Rescorla F , et al.   Outcome and staging evaluation in malignant germ cell tumors of the ovary in children and adolescents (an intergroup study) . J Pediatr Surg . 2004;39:424–429
  5. Tsuchida Y , Endo Y , Saito S , et al.   Evaluation of alpha-fetoprotein in early infancy . J Pediatr Surg . 1978;13:155–156
  6. Heifetz S , Cushing B , Giller R , et al.   Immature teratomas in children: pathologic considerations: a report from the combined pediatric oncology group/Children’s Cancer Group . Am J Surg Pathol . 1998;22:1115–1124
  7. Baker B , Frickey L , Yu I-T , et al.   DNA content of ovarian immature teratomas and malignant germ cell tumors . Gynecol Oncol . 1998;71:14–18
  8. Cushing B , Giller R , Ablin A , et al.   Surgical resection alone is effective treatment for ovarian immature teratoma in children and adolescents (a report of the Pediatric Oncology Group and Children’s Cancer Group) . Am J Obstet Gynecol . 1999;181:353–358
  9. Marina N , Cushing B , Giller R , et al.   Complete surgical excision is effective treatment for children with immature teratomas with or without malignant elements (a Pediatric Oncology Group/Children’s Cancer Group intergroup study) . J Clin Oncol . 1999;17:2137–2143
  10. Charoenkwan P , Senger C , Weitzman S , et al.   Significance of p53 expression in immature teratomas . Pediatr Dev Pathol . 2002;5:499–507
  11. Yanai H , Matsuura H , Kawasaki M , et al.   Immature teratoma of the ovary with a minor rhabdomyosarcomatous component and fatal rhabdomyosarcomatous metastases (the first case in a child) . Int J Gynecol Pathol . 2002;21:82–85
  12. Block M , Gilbert E , Davis C . Metastatic neuroblastoma arising in an ovarian teratoma with long-term survival . Cancer . 1984;54:590–595
  13. Culine S , Lhomme C , Kattan J , et al.   Pure malignant immature teratoma of the ovary (the role of chemotherapy and second-look surgery) . Int J Gynecol Cancer . 1995;5:432–437
  14. Baranzelli MC , Bouffet E , Quintana E , et al.   Non-seminomatous ovarian germ cell tumours in children . Eur J Cancer . 2000;35:376–383
  15. Terenziani M , Massimino M , Casanova M , et al.   Childhood malignant ovarian germ cell tumors (a monoinstitutional experience) . Gynecol Oncol . 2001;81:436–440
  16. Einhorn LH , Donohue J . Cis-diamminedichloroplatinum, vinblastine and bleomycin combination chemotherapy IV disseminated testicular cancer . Ann Int Med . 1977;87:293–298
  17. Baranzelli MC , Flamant F , De Lumley L , et al.   Treatment of non-metastatic, non-seminomatous malignant germ-cell tumour in childhood (experience of the “Société Française d’Oncologie Pédiatrique” MGCT 1985-1989 study) . Med Pediatr Oncol . 1993;21:395–401
  18. Mann JR , Raafat F , Robinson K , et al.   The United Kingdom Children’s Cancer Study Group’s second germ cell tumor study (carboplatin, etoposide, and bleomycin are effective treatment for children with malignant extracranial germ cell tumors, with acceptable toxicity) . J Clin Oncol . 2000;18:3809–3818
  19. Göbel U , Schneider DT , Calaminus G , et al.   Multimodal treatment of malignant sacrococcygeal germ cell tumors (a prospective analysis of 66 patients of the German Cooperative Protocols MAKEI 83/86 and 89) . J Clin Oncol . 2001;19:1943–1950
  20. Ablin AR , Krailo MD , Ramsay MKC , et al.   Results of treatment of malignant germ cell tumors in 93 children (a report from the Children’s Cancer Study Group) . J Clin Oncol . 1991;9:1782–1792
  21. Cushing B , Giller R , Cullen JW , et al.   Randomized comparison of combination chemotherapy with etoposide, bleomycin, and either high-dose or standard dose cisplatin in children and adolescents with high-risk malignant germ cell tumors (a pediatric intergroup study-Pediatric Oncology Group 9049 and Children’s Cancer Group 8882) . J Clin Oncol . 2004;22:2691–2700
  22. Malone PS , Spitz L , Kiely EM , et al.   The functional sequelae of sacrococcygeal teratoma . J Pediatr Surg . 1990;25:679–680
  23. Schmidt P , Haas RJ , Göbel U , et al.   Results of the German studies (MAHO) for treatment of testicular germ cell tumors in children-an update . Klin Padiatr . 2002;214:167–172
  24. Schlatter M , Rescorla F , Giller R , et al.   Excellent outcome in patients with stage I germ cell tumors of the testes (a study of the Children’s Cancer Group/Pediatric Oncology Group) . J Pediatr Surg . 2003;38:319–324
  25. Rescorla F , Billmire D , Stolar C , et al.   The effect of cisplatin dose and surgical resection in children with malignant germ cell tumors at the sacrococcygeal region (a pediatric intergroup trial (POG 9049/CCG 882)) . J Pediatr Surg . 2001;36:12–17
  26. Logothesis CJ , Samuels ML , Trividale A , et al.   The growing teratoma syndrome . Cancer . 1982;50:1629–1635
  27. Perlman EJ , Hu J , Ho D , et al.   Genetic analysis of childhood endodermal sinus tumors by comparative genomic hybridization . J Pediatr Hematol Oncol . 2000;22:100–105
  28. Schneider DT , Schuster AE , Fritsch MK , et al.   Genetic analysis of childhood germ cell tumors with comparative genomic hybridization . Klin Padiatr . 2001;213:204–211
  29. Rescorla FJ , Sawin RS , Coran AG , et al.   Long-term outcome for infants and children with sacrococcygeal teratoma (a report from the Childrens Cancer Group) . J Pediatr Surg . 1998;22:171–176
  30. Zanetta G , Bonazzi C , Cantù MG , et al.   Survival and reproductive function after treatment of malignant germ cell ovarian tumors . J Clin Oncol . 2001;19:1015–1020
  31. Kanazawa K , Suzuki T , Sakumoto K . Treatment of malignant ovarian germ cell tumors with preservation of fertility (a reproductive performance after persistent remission) . Am J Clin Oncol . 2000;23:244–248
  32. Ciftci AO , Bingol-Kologlu M , Senocak ME , et al.   Testicular tumors in children . J Pediatr Surg . 2001;36:1796–1801
  33. Metcalfe PD , Farivar-Mohseni H , Earhart W , et al.   Pediatric testicular tumors (a contemporary incidence and efficacy of testicular preserving surgery) . J Urol . 2003;170:2412–2416
  34. Billmire D , Vinocur C , Rescorla F , et al.   Malignant retroperitoneal and abdominal germ cell tumors (an intergroup study) . J Pediatr Surg . 2003;38:315–318
  35. Rescorla F , Billmire D , Vinocur C , et al.   The effect of neoadjuvant chemotherapy and surgery in children with malignant germ cell tumors of the genital region (a pediatric intergroup trial) . J Pediatr Surg . 2003;38:910–912

PII: S1055-8586(05)00091-0

doi: 10.1053/j.sempedsurg.2005.11.006

Seminars in Pediatric Surgery
Volume 15, Issue 1 , Pages 30-36 , February 2006

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