Seminars in Pediatric Surgery
Volume 15, Issue 1 , Pages 25-29 , February 2006

Management of osteosarcoma pulmonary metastases

  • Matthew T. Harting, MD

      Affiliations

    • Department of Surgery, University of Texas Health Science Center, Houston, TX
  • ,
  • Martin L. Blakely, MD

      Affiliations

    • Departments of Surgery and Pediatrics, University of Tennessee Health Science Center, Memphis, TN
    • Corresponding Author InformationAddress reprint requests and correspondence: Martin L. Blakely, MD, Pediatric Surgery, University of Tennessee Health Science Center, 777 Washington Avenue, P220, Memphis, TN 38105

References 

  1. Gurney JG , Swensen AR , Bulterys M . Malignant bone tumors . In:  Ries LAG ,  Smith MA ,  Gurney JG editor. Cancer Incidence and Survival Among Children and Adolescents (United States SEER Program 1975-1995 (NIH Publ. No. 99-4649)) . Bethesda, MD: National Cancer Institute; 1999;p. 99–110
  2. Dahlin DC , Unni KK . Osteosarcoma of bone and its important recognizable varieties . Am J Surg Pathol . 1977;1:61–72
  3. Yasko AW . Osteosarcoma and other bone tumors . In:  Andrassy RJ editors. Pediatric Surgical Oncology (chap. 23) . Philadelphia, PA: WB Saunders Co; 1998;p. 419–448
  4. Link MP , Gebhardt MC , Meyers PA . Osteosarcoma . In:  Pizzo PA ,  Poplack DG editor. Principles and Practice of Pediatric Oncology (chap. 35) . Baltimore, MD: Lippincott Williams and Wilkins; 2002;p. 1051–1089
  5. Goorin AM , Harris MB , Bernstein M , et al.   Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma (a pediatric oncology group trial) . J Clin Oncol . 2002;20:426–433
  6. Ferguson WS , Harris MB , Goorin AM , et al.   Presurgical window of carboplatin and surgery and multidrug chemotherapy for the treatment of newly diagnosed metastatic or unresectable osteosarcoma (Pediatric Oncology Group Trial) . J Pediatr Hematol Oncol . 2001;23:340–348
  7. Han MT , Telander RL , Pairolero PC , et al.   Aggressive thoracotomy for pulmonary metastatic osteogenic sarcoma in children and young adolescents . J Pediatr Surg . 1981;16:928–933
  8. Goorin AM , Delorey MJ , Lack EE , et al.   Prognostic significance of complete surgical resection of pulmonary metastases in patients with osteogenic sarcoma (analysis of 32 patients) . J Clin Oncol . 1984;2:425–431
  9. Ward WG , Mikaelian K , Dorey F , et al.   Pulmonary metastases of stage IIB extremity osteosarcoma and subsequent pulmonary metastases . J Clin Oncol . 1994;12:1849–1858
  10. Castagnetti M , Delarue A , Gentet JC . Optimizing the surgical management of lung nodules in children with osteosarcoma (thoracoscopy for biopsies, thoracotomy for resections) . Surg Endosc . 2004;18:1668–1671
  11. Margaritora S , Porziella V , D’Andrilli A , et al.   Pulmonary metastases (can accurate radiological evaluation avoid thoracotomic approach?) . Eur J Cardiothorac Surg . 2002;21:1111–1114
  12. McCarville MB , Kaste SC , Cain AM , et al.   Prognostic factors and imaging patterns of recurrent pulmonary nodules after thoracotomy in children with osteosarcoma . Cancer . 2001;91:1170–1176
  13. Picci P , Vanel D , Briccoli A , et al.   Computed tomography of pulmonary metastases from osteosarcoma: the less poor technique. A study of 51 patients with histological correlation . Ann Oncol . 2001;12:1601–1604
  14. Franzius C , Daldrup-Link HE , Sciuk J , et al.   FDG-PET for detection of pulmonary metastases from malignant primary bone tumors (comparison with spiral CT) . Ann Oncol . 2001;12:479–486
  15. Kempf-Bielack B , Bielack SS , Jurgens H , et al.   Osteosarcoma relapse after combined modality therapy (an analysis of unselected patients in the Cooperative Osteosarcoma Study Group (COSS)) . J Clin Oncol . 2005;23:559–568
  16. Hawkins DS , Arndt CA . Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy . Cancer . 2003;98:2447–2456
  17. Kager L , Zoubek A , Potschger U , et al.   Primary metastatic osteosarcoma (presentation and outcome of patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols) . J Clin Oncol . 2003;21:2011–2018
  18. Harting MT , Blakely ML , Jaffe N , et al.   Long-term survival after aggressive resection of pulmonary metastases among children and adolescents with osteosarcoma . J Pediatr Surg . 2005; in press
  19. Winkler K , Beron G , Kotz R , et al.   Neoadjuvant chemotherapy for osteogenic sarcoma (results of a cooperative German/Austrian study) . J Clin Oncol . 1984;2:617–624
  20. Hudson M , Jaffe MR , Jaffe N , et al.   Pediatric osteosarcoma (Therapeutic strategies, results, and prognostic factors derived from a 10-year experience) . J Clin Oncol . 1990;8:1988–1997
  21. Glasser DB , Lane JM , Huvos AG , et al.   Survival, prognosis, and therapeutic response in osteogenic sarcoma. The Memorial Hospital experience . Cancer . 1992;69:698–708
  22. Bielack SS , Kempf-Bielack B , Delling G , et al.   Prognostic factors in high-grade osteosarcoma of the extremities or trunk (an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols) . J Clin Oncol . 2002;20:776–790
  23. French Bone Tumor Study Group . Age and dose of chemotherapy as major prognostic factors in a trial of adjuvant therapy of osteosarcoma combining two alternating drug combinations and early prophylactic lung irradiation . Cancer . 1988;61:1304–1311
  24. Ferrari S , Bertoni F , Mercuri M , et al.   Predictive factors of disease-free survival for non-metastatic osteosarcoma of the extremity (an analysis of 300 patients treated at the Rizzoli Institute) . Ann Oncol . 2001;12:1145–1150
  25. Crompton BD , Goldsby RE , Weinberg VK , et al.   Survival after recurrence of osteosarcoma (A 20-year experience at a single institution) . Pediatr Blood Cancer . 2005; Aug 25 [Epub ahead of print]
  26. Briccoli A , Rocca M , Salone M , et al.   Resection of recurrent pulmonary metastases in patients with osteosarcoma . Cancer . 2005; Sept 9 [Epub ahead of print]
  27. Ferrari S , Briccoli A , Mercuri M , et al.   Postrelapse survival in osteosarcoma of the extremities (prognostic factors for long-term survival) . J Clin Oncol . 2003;21:710–715
  28. Tsuchiya H , Kanazawa Y , Abdel-Wanis ME , et al.   Effect of timing of pulmonary metastases identification on prognosis of patients with osteosarcoma (the Japanese Musculoskeletal Oncology Group study) . J Clin Oncol . 2002;20:3470–3477
  29. Dhaini HR , Thomas DG , Giordano TJ , et al.   Cytochrome P450 CYP3A 4/5 expression as a biomarker of outcome in osteosarcoma . J Clin Oncol . 2003;21:2481–2485
  30. Zhou H , Randall RL , Brothman AR , et al.   Her-2/neu expression in osteosarcoma increases risk of lung metastasis and can be associated with gene amplification . J Pediatr Hematol Oncol . 2003;25:27–32
  31. Scotlandi K , Manara MC , Hattinger CM , et al.   Prognostic and therapeutic relevance of HER2 expression in osteosarcoma and Ewing’s sarcoma . Eur J Cancer . 2005;41:1349–1361
  32. Sanders RP , Drissi R , Billups CA , et al.   Telomerase expression predicts unfavorable outcome in osteosarcoma . J Clin Oncol . 2004;22:3790–3797
  33. Akatsuka T , Wada T , Kokai Y , et al.   Erb B2 expression is correlated with increased survival of patients with osteosarcoma . Cancer . 2002;94:1397–1404
  34. Su WT , Chewning J , Abramson S , et al.   Surgical management and outcome of osteosarcoma patients with unilateral pulmonary metastases . J Pediatr Surg . 2004;39:418–423
  35. Ambrogi V , Paci M , Pompeo E , et al.   Transxiphoid video-assisted pulmonary metastasectomy (relevance of helical computed tomography occult lesions) . Ann Thorac Surg . 2000;70:1847–1852
  36. De Oliveira-Filho AG , Neto LS , Epelman S . Median sternotomy for the resection of bilateral pulmonary metastases in children . Pediatr Surg Int . 1998;13:560–563
  37. Pastorino U , Valente M , Gasparini M , et al.   Median sternotomy and multiple lung resections for metastatic sarcomas . Eur J Cardiothorac Surg . 1990;4:477–481
  38. Johnston MR . Median sternotomy for resection of pulmonary metastases . J Thorac Cardiovasc Surg . 1983;85:516–522
  39. Rothenberg SS . Thoracoscopic lung resection in children . J Pediatr Surg . 2000;35:271–274
  40. Watanabe M , Deguchi H , Sato M , et al.   Midterm results of thoracoscopic surgery for pulmonary metastases especially from colorectal cancers . J Laparoendosc Adv Surg Tech A . 1998;8:195–200

PII: S1055-8586(05)00090-9

doi: 10.1053/j.sempedsurg.2005.11.005

Seminars in Pediatric Surgery
Volume 15, Issue 1 , Pages 25-29 , February 2006