Seminars in Pediatric Surgery
Volume 14, Issue 2 , Pages 118-123 , May 2005

Evaluation and management of the abnormal gonad

  • Sandeep S. Bidarkar, DNB, MCh

      Affiliations

    • Department of General Surgery, Royal Children’s Hospital, Parkville, Victoria, Australia
    • ,
  • John M. Hutson, Prof., MD (FAAP)

      Affiliations

    • Department of General Surgery, Royal Children’s Hospital, Parkville, Victoria, Australia
    • Murdoch Children’s Research Institute, Parkville, Victoria, Australia
    • Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia
    • Corresponding Author InformationAddress reprint requests and correspondence: Prof. John M. Hutson, MD, Royal Children’s Hospital, Flemington Road, Parkville, Victoria 3052 Australia.

References 

  1. Skandalakis JE , Gray SW , Parrott TS , et al.   The ovary and testis . In:  Skandalakis JE ,  Gray SW editor. Embryology for Surgeons . (ed 2). London: Williams and Wilkins; 1993;p. 736–772 chap 31
  2. Sadler TW . Gonads (urogenital system) . In:  Sadler TW , et al. editor. Langman’s Medical Embryology . (ed 5). London: Williams and Wilkins; 1995;p. 247–280 chap 15
  3. Donahoe PK , Schnitzer JJ . Ambiguous genitalia in the newborn . In:  O’Neil JA ,  Rowe MI ,  Grosfeld JL , et al. editor. (ed 5). Pediatric Surgery . Vol. 2: St. Louis, MO: Mosby; 1998;p. 1797–1818 chap 118
  4. Gondos B . Diagnosis of abnormalities in gonadal development . Ann Clin Lab Sci . 1982;12:276–287
  5. Rohatgi M . Intersex disorders (an approach to surgical management) . Indian J Pediatr . 1992;59:523–530
  6. Forest MG . Etiopathogenesis, classification, investigation and diagnosis in intersex disorders . Indian J Pediatr . 1992;59:475–485
  7. Donahoe PK , Schnitzer JJ . Evaluation of the infant who has ambiguous genitalia, and principles of operative management . Semin Pediatr Surg . 1996;1:30–40
  8. Coran AG . Surgical management of ambiguous genitalia in the infant and child . J Pediatr Surg . 1991;8:12–20
  9. Reiner WG . Sex assignment in the neonate with intersex or inadequate genitalia . Arch Pediatr Adolesc Med . 1997;151:1044–1045
  10. Slowikowska HJ , Szarras CM , Kula K . Testicular pathology in 46, XY dysgenetic male pseudohermaphroditism (an approach to pathogenesis of testicular cancer) . J Androl . 2001;22:781–792
  11. Krstic ZD , Smoljanic Z , Vukanic D , et al.   True hermaphroditism (10 year’s experience) . Pediatr Surg Int . 2000;16:580–583
  12. Kaefer M , Diamond D , Hendren WH , et al.   The incidence of intersexuality in children with cryptorchidism and hypospadias (stratification based on gonadal palpability and meatal position) . J Urol . 1999;162:1003–1007
  13. Levin HS . Tumors of the testis in intersex syndromes . Urol Clin North Am . 2000;27:543–551
  14. Gupta DK , Menon PS . Ambiguous genitalia (an Indian perspective) . Indian J Pediatr . 1997;64:189–194
  15. Migeon CJ , Wisniewski AB , Gearhart JP , et al.   Ambiguous genitalia with perineoscrotal hypospadias in 46,XY individuals (long term medical, surgical, and psychosexual outcome) . Pediatrics . 2002;110:e31
  16. Daaboul J , Frader J . Ethics and the management of the patient with intersex (a middle way) . J Pediatr Endocrinol Metab . 2001;14:1575–1583
  17. Lee PA . A perspective on the approach to the intersex child born with genital ambiguity . J Pediatr Endocrinol Metab . 2004;17:133–140
  18. Esegbona G , Cutner A , Cuckow P , et al.   Laparoscopic gonadectomy in paediatric and adolescent girls with intersex disorders . BJOG . 2003;110:210–212
  19. Hutson JM, Kimber C. Laparoscopy for intersex: operative endoscopy and endoscopic surgery in infants and children. In: Najmaldin A, Rothenberg S, Crabbe D, et al, eds. London: Edward Arnold, in press.
  20. Hrabovszky Z , Hutson JM . Androgen imprinting of the brain in animal models and humans with intersex disorders. Review and recommendations . J Urol . 2002;168:2142–2148
  21. Low Y , Hutson JM  MCRI Sex Study Group . The rules for clinical diagnosis in babies with ambiguous genitalia . J Paediatr Child Health . 2003;39:406–413
  22. Hrabovszky Z , Hutson JM . Surgical treatment of intersex anomalies (a review) . Surgery . 2002;131:92–104

PII: S1055-8586(05)00014-4

doi: 10.1053/j.sempedsurg.2005.01.008

Seminars in Pediatric Surgery
Volume 14, Issue 2 , Pages 118-123 , May 2005

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