Seminars in Pediatric Surgery
Volume 12, Issue 1 , Pages 17-37, February 2003

New concepts in the pathology of congenital lung malformations☆

Department of Pathology, Texas Children's Hospital and the Department of Pathology, Baylor College of Medicine, Houston, TX. Houston, Texas

Abstract 

Focal developmental malformations of the lung are a heterogeneous group of lesions that display a variety of features. They often are thought to be quite distinct entities, but there is considerable overlap among these lesions. Both standard nomenclature and common usage do not identify clearly the components of these lesions in a distinctive fashion. A classification based on pathologic features is presented. A malformation sequence based on airway obstruction during development is proposed as a unifying pathogenetic mechanism for some seemingly unrelated lesions. Copyright 2003, Elsevier Science (USA). All rights reserved.

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☆ Address reprint requests to Claire Langston, MD, Department of Pathology, Texas Children's Hospital, 6621 Fannin St, Houston, TX 77030.

PII: S1055-8586(03)70004-3

Seminars in Pediatric Surgery
Volume 12, Issue 1 , Pages 17-37, February 2003

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